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Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation

Fig. 1

Cordyceps militaris extract dose-dependently inhibits viability and induces morphological changes in SKOV-3 cells (mixed type of HGSC, clear cell, and endometrioid). (a) SKOV-3 cells were exposed to 0 (vesicle), 62.5, 125, 250, 500, and 1000 μg/mL C. militaris extract for 24 and 48 h before estimation of cell number using the CCK-8 assay. The experiment was performed in triplicate. C. militaris significantly inhibited cell proliferation of SKOV-3 ovarian cancer cells. (b) Morphological changes of SKOV-3 were treated with C. militaris (125, 250, 500, and 1000 μg/mL) compared with control (vehicle). Magnification × 400. The statistics demonstrated that the percentage of the cells mainly represents treated cells, which was apparent when the percentage of control cells markedly decreased. Data are presented as means ± standard deviations from triplicate experiments. Statistical significance was considered that * means p < 0.05, ** means p < 0.01, *** p < 0.001, and ns means non-significance

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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