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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation

Fig. 5

Morphological changes in the ultrastructural appearance of apoptotic bodies in CME-treated ovarian cancer cells with transmission electron microscopy (TEM). a Untreated SKOV-3 and (b) CME-treated SKOV-3 cells (500 μg/mL CME concentration) were analyzed by TEM after 24 h. The typical apoptotic bodies in CME-treated cells were observed as spherical protuberances containing fragmented and segregated chromatin clumps separated from cell surface. Mitochondrial disruption and autophagosomes were observed in CME-treated SKOV-3 cells. Representative images are shown

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