Fig. 4

Microscopic images of articular tissue of rats at the 14th day after intra-articular injection (n = 3 in each group). Hematoxylin and Eosin staining, 100X. a The control group (no change), b the osteoarthritis group (severe hypertension and tissue analysis), c the osteoarthritis received gel contained the nanoemulsion group, d the osteoarthritis received gel contained Mentha and Rosemary essential oils group, e the osteoarthritis received the nanoemulsion solution group, and f the osteoarthritis received gel contained 1% diclofenac sodium group