Fig. 2

Impaired mitochondrial morphology and function were rescued by Tan IIA. (A) The morphology of mitochondria in the renal tissue. Control group and Tan IIA treatment groups at 0 h displayed an intact structure with clear cristae, however, fewer cristae were observed in the mitochondria in the control group after 24 h and 48 h of hypothermic preservation, and Tan IIA treatment preserved more intact mitochondria with discernable cristae. Scale bar: 1 μm. Mitochondrial ATP production (B) and mitochondrial membrane permeability (C) were partially reduced by Tan IIA. ns > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001; n = 5