Fig. 5

Relative mRNA and protein expression of key factors in the TLR7 signaling pathway. A Represent the relative expression of TLR7, Myd88 and NF-κB mRNA in the TLR7 signaling pathway in WT mice and TLR7^−/− mice (n = 3); B shows the expression of TLR7, Myd88, and NF-κB proteins in WT mice and TLR7^−/− mice; C and D show statistical graphs of TLR7, Myd88, and NF-κB protein expression in WT mice and TLR7.^−/− mice (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, NS = not significant, P > 0.05