Fig. 6From: Ginsenoside Rg-1 prevents elevated cytosolic Ca2+ via store-operated Ca2+ entry in high-glucose–stimulated vascular endothelial and smooth muscle cellsEffects of Ni2+ and KB-R7943 on Rg-1–induced increases in SOCE in EA and MOVAS cells exposed to high glucose. A & B Representative traces showing the effects of high glucose, high glucose plus 100 nM Ni2+, high glucose plus 10 μM KB-R7943, high glucose plus 10 μM Rg-1, high glucose plus 10 μM Rg-1 and 100 nM Ni2+, and high glucose plus 10 μM Rg-1 and 10 μM KB-R7943 on SOCE in (A) EA and (B) MOVAS cells. C Summary data showing area under the curve (AUC) values for 500 seconds for EA and MOVAS cells. The symbol (▼) indicates the time point at which 30 μM BHQ was applied. Data are means ± SEM (n = 6–12; #p < 0.05, ##p < 0.01 compared with high glucose; *p < 0.05, **p < 0.01 compared with high glucose plus Rg-1)Back to article page