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Table 2 Effect of genistein on MPO, NF-kB, 4-HNE expression and acinar cell apoptosis in acute pancreatitis mice

From: Genistein attenuated oxidative stress, inflammation, and apoptosis in L-arginine induced acute pancreatitis in mice

Groups (n = 6)

Parameters

MPO positive (cells of HPF)

NF-kB Positive cells (%)

4-HNE Positive cells (%)

TUNEL Positive cells (%)

Con

0.33 ± 0.08

0.44 ± 0.01

0.40 ± 0.02

0.07 ± 0.01

AP

21.00 ± 4.60a1

0.75 ± 0.01a1

0.76 ± 0.01a1

0.22 ± 0.01a1

LG

4.13 ± 0.73b1

0.47 ± 0.01a2,b1

0.45 ± 0.01a2,b1

0.09 ± 0.00a2,b1

HG

2.97 ± 0.44b1

0.46 ± 0.01b1

0.43 ± 0.01b1

0.07 ± 0.00b1

  1. Data are express as mean ± SEM. a1p < 0.01, a2p < 0.05 vs. Con group; b1p < 0.01, b2p < 0.05 vs. AP group
  2. Abbreviations: Con Control group, AP Acute pancreatitis group, LG Low dose of genistein group, HG High dose of genistein group, MPO Myeloperoxidase, NF-kB Nuclear factor-kappa beta, 4-HNE 4-Hydroxynonenal, TUNEL Terminal deoxynucleotidyl transferase dUTP nick end labeling
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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