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Table 5 Pharmacokinetics parameters for six compounds (mean ± SD, n = 6)

From: Pharmacokinetics and pharmacodynamics of bioactive compounds in Penyanqing preparation in THP-1 inflammatory cells induced by Lipopolysaccharide

Parameter

Unit

AST

CH

FE

PE

PRO

SAB

AUC(0-t)

mg/L*h

2.08 ± 0.20

0.92 ± 0.06

1.43 ± 0.23

2.21 ± 0.31

1.05 ± 0.06

3.40 ± 0.45

AUC(0-∞)

mg/L*h

2.09 ± 0.20

0.94 ± 0.09

1.48 ± 0.24

2.22 ± 0.31

1.08 ± 0.07

3.70 ± 0.46

t1/2

h

3.42 ± 0.34

1.86 ± 0.21

0.90 ± 0.02

2.37 ± 0.20

0.93 ± 0.06

7.60 ± 3.34

tmax

h

0.25 ± 0

0.25 ± 0

0.25 ± 0

0.25 ± 0

0.25 ± 0

0.29 ± 0.10

CLz/F

L/h/kg

9.55 ± 0.81

21.33 ± 1.29

13.80 ± 2.37

9.15 ± 1.27

18.57 ± 1.07

5.48 ± 0.68

Vz/F

L/kg

45.37 ± 6.31

57.19 ± 7.48

17.85 ± 3.28

31.26 ± 4.08

24.94 ± 1.96

59.83 ± 25.48

Cmax

mg/L

2.27 ± 0.35

1.37 ± 0.06

1.20 ± 0.15

2.04 ± 0.59

1.43 ± 0.22

1.59 ± 0.33