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Table 1 Combination index of interaction between DHA and GIE against PbANKA-infected mice

From: Synergistic antimalarial treatment of Plasmodium berghei infection in mice with dihydroartemisinin and Gymnema inodorum leaf extract

Test

Dose (mg/kg)

CI value

DHA

GIE

Combination

100/0

2

0

-

80/20

1.6

20

1.70625b

60/40

1.2

40

0.68695a

40/60

0.8

60

1.48699b

20/80

0.4

80

3.65127b

0/100

0

100

-

  1. DHA dihydroartemisinin, GIE Gymnema inodorum extract, CI combination inde
  2. a CI < 1; synergism, b CI > 1; antagonism