Defining the landscape of patient harm after osteopathic manipulative treatment: synthesis of an adverse event model

Table 3 Model parameters extracted from studies that passed methodological review

Study reference number	AE severity^a	AEs preceded by an OMT encounter	OMT encounters with post-OMT interval assessment	Post-OMT interval (days)	Cumulative incidence of post-OMT AEs^b	Post-OMT interval-days^c
[22]	Mild	0	10	1	0.0	10
	Moderate	0
	Severe	0
[6]	Mild	45	1847	1	2.4	1847
	Moderate	0
	Severe	0
[23]	Mild	1	29	1	3.4	29
	Moderate	0
	Severe	0
[24]	Mild	2	10	1	20	10
	Moderate	0
	Severe	0
[11]	Mild	13	93	1	14	93
	Moderate	0
	Severe	0
[9]	Mild	2	17	1	11.8	17
	Moderate	0
	Severe	0
[25]	Mild	1	109	3	0.9	327
	Moderate	0
	Severe	0
[10]	Mild	4	63	3	11.1	189
	Moderate	3
	Severe	0
[26]	Mild	0	18	7	0.0	126
	Moderate	0
	Severe	0
[19]	Mild	36	298	7	12	2086
	Moderate	0
	Severe	1
[27]	Mild	39	66	7	59	462
	Moderate	0
	Severe	0
[28]	Mild	8	72	7	11.1	504
	Moderate	0
	Severe	0
[29]	Mild	10	1146	9	0.9	10,314
	Moderate	0
	Severe	0
Variables, formulae		X	Y	Z	([total X]/Y)*100%	Y*Z

Legend: ^aEach AE reported in the literature was classified as an AE whether or not a causal relationship between the adverse patient outcome and preceding OMT encounter was reported. AE severity grades “life-threatening” and “death” are omitted from the table as no AEs were observed in either category across all modeled studies. ^bCumulative incidence of post-OMT AEs for each study was calculated as follows: ([total X]/Y)*100%. Cumulative incidence for each study was calculated across all AEs regardless of AE severity. ^cPost-OMT interval-days for each study was calculated as follows: Y*Z. AE Adverse event, OMT Osteopathic manipulative treatment

ISSN: 2662-7671