Fig. 3

Effect of AP and andrographolide on oxidative stress markers and Tau protein in alchor/D-gal induced AD mice. The SOD activity and MDA content in serum(A-B) and brain tissue(C-D) were determined by commercially-available kits. Values are mean ± SD (n = 8–10) (E) The expression levels of Tau and P-Tau in the hippocampus were examined by western blot, and GAPDH was served as a loading control. (F) Quantitative analysis of P-Tau/Tau protein expression.Values are mean ± SD (n = 6–8). ^*P < 0.05, ^***P < 0.001 vs. normal group, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. model group, ⁺P < 0.05, ⁺⁺P < 0.05 vs. donepezil group