Therapeutic effect of curcumin nanoemulsion on cystic echinococcosis in BALB/c mice: a computerized tomography (CT) scan and histopathologic study evaluation

Table 2 Mean ± SD cyst area before and 60 days after treatment in different BALB/c groups

Groups	n	Cyst area (mm) using digimizer measurement		Cyst area (mm) using CT scan measurement
		Mean ± SD before treatment	Mean ± SD after treatment	Mean ± SD before treatment	Mean ± SD after treatment	P value (Student’s t-test)
CEI1: treated with curcumin nanoemulsion (CUR-NE) (40 mg/kg/day)	6	Lack of access to secondary cysts	30.33 ± 21.91	25.83 ± 6.8	23.66 ± 6.25	0.063
CEI2: treated with CUR-NE (20 mg/kg/day)	6	Lack of access to secondary cysts	49.83 ± 18.11	24.83 ± 6.46	26.58 ± 8.02	0.499
CEI3: treated with NE without CUR (NE-no CUR)	6	Lack of access to secondary cysts	57.5 ± 25.28	29.5 ± 9.93	29.66 ± 10.52	0.95
CEI4: treated with curcumin suspension (CUR-S) (40 mg/kg/day)	6	Lack of access to secondary cysts	35.66 ± 20.81	27.3 ± 5.56	26.6 ± 7.17	0.75
CEI5: treated with ABZ (150 mg/kg/day) (PC¹)	6	Lack of access to secondary cysts	50.66 ± 20.37	26.16 ± 7.74	24.58 ± 7.39	0.217
CEI6: received sterile PBS (NC²)	4	Lack of access to secondary cysts	67.75 ± 28.84	24.41 ± 6.64	26.41 ± 8.08	0.033^*

ISSN: 2662-7671